As the coronavirus continues to evolve, a new highly contagious Omicron variant is appearing in India and other nations, including the United States, experts say.. BA.2 Symptoms Not That Different From Omicron, Delta. Genomes have now been uploaded from South Africa, Botswana and Hong Kong but the extent of spread is not yet determined. A BA2 variant's symptoms are similar to those of Omicron. We now know that BA.2 has an increased growth rate which can be seen in all regions in England. More detail will be available in UKHSAs regular variant technical briefings. XBB.1.5 remains at very low prevalence in the UK, so estimates of growth are highly uncertain. 2023 BBC. The vaccination status was unknown for 6 people, while 8 had received a single dose. Updated analysisshows theadditional incremental benefit from each vaccine exposureincluding for boosters, even in those who have had prior infection. You can change your cookie settings at any time. However, it is not confirmatory as there are a number of other reasons that a sample might exhibit SGTF. According to the COVID Symptom Study, the five most common symptoms are the same: Runny nose, headache, fatigue, sneezing and sore throat. Cases are currently very high in the UK, and even a relatively low proportion requiring hospitalisation could result in a significant number of people becoming seriously ill. Of 5,153 individuals identified with an Omicron infection between 1 November and 11 December 2021, 305 were linked to a previous confirmed infection and had an interval from the previous positive test of 90 days or more. While BA.2 appears to be more transmissible than previous variants, there is no data yet to suggest that it is any more severe. "Looking at other countries where BA.2 is now overtaking, we're not seeing any higher bumps in hospitalisation than expected," the WHO's Dr Boris Pavlin says. Prior infection is 44% effective at preventing future infection, increasing to 71% with 3 doses of the vaccine. UKHSA continues to monitor and study variants of SARS-CoV-2 closely and is working with academic partners to rapidly assess the significance of the lineages BA.4 and BA.5. There can be several reasons for growth advantage, but in the case of BA.4 and BA.5, laboratory data suggests a degree of immune escape which is likely to contribute. Neither have been designated as variants of concern by UKHSA. The UK Health Security Agency (UKHSA) has identified 2 further cases of COVID-19 with mutations consistent with B.1.1.529 in England, in addition to the previous 3 confirmed cases of the SARS-CoV-2 variant known as B.1.1.529 on 27 and 28 November. Currently, no experimental data has been reported about BA.2 and BA.3. Thats why its critical that anyone with COVID-19 symptoms isolates and gets a PCR test immediately. While evidence is still emerging, so far it does not appear this variant causes more severe disease or renders the vaccines currently deployed any less effective. UKHSA will continue to monitor the situation closely as a matter of routine, as we do all data relating to SARS-CoV-2 variants both in the UK and internationally. Working from home where possible, consistently wearing masks in crowded or enclosed spaces, washing your hands regularly and isolating and getting tested if you feel unwell are also vitally important in reducing the impact of COVID-19 this winter. UKHSA are continuing to monitor data on the BA.2 sub-lineage closely. One individual diagnosed in hospital has sadly died. When the reduced risk of hospitalisation was combined with vaccine effectiveness against symptomatic disease, the vaccine effectiveness against hospitalisation was estimated as 52% after one dose, 72% 2 to 24 weeks after dose 2, 52% 25+ weeks after dose 2 and 88% 2 weeks after a booster dose. It is very likely that we will find more cases over the coming days as we are seeing in other countries globally and as we increase case detection through focussed contact tracing. Everybody who is contacted or has symptoms should take a PCR test as soon as possible, even if they have received a positive COVID-19 PCR test within the last 90 days. These are potentially biologically significant mutations which may change the behaviour of the virus with regards to immune escape, transmissibility or susceptibility to treatments, but this has not been proven. For some more vulnerable a third dose is available. As we learn to live safely with COVID-19, there are actions we can all take to help reduce the risk of catching COVID-19 and passing it on to others. The early observations for 2 doses of AstraZeneca are particularly likely to be unreliable as they are based on small numbers and are likely to reflect an older population and a population with more co-morbidities than those given the Pfizer vaccine. Omicron has a deletion atposition69/70of the spike proteinwhich allows it to be tracked through S gene target failure(SGTF)in some PCR tests. Vaccination remains our best defence against future COVID-19 waves, so it is still as important as ever that people come take up all the doses for which they are eligible as soon as possible. Six cases of the SARS-CoV-2 variant known as B.1.1.529 have also been identified in Scotland, with 4 cases in the Lanarkshire area and 2 in the Greater Glasgow and Clyde area. So how worried should we be about this emerging variant? Omicron BA.2 Variant Severity These are some of the symptoms that you should be looking out for: High temperature. It was designated a variant of concern (VOC) on Saturday 27 November. I urge you to come forward as soon as youre eligible to help keep yourself and your loved ones safe. Thats why its critical that anyone with COVID-19 symptoms isolates and gets aPCRtest immediately. There are simple things you can do in your daily life that will help reduce the spread of COVID-19 and other respiratory infections and protect those at highest risk. Further information is also available in the latest variant technical briefing. An individual with Omicron is estimated to be between 31 and 45% less likely to attend A&E compared to Delta, and 50 to 70% less likely to be admitted to hospital. Analyses of sequenced SGTF samples has indicated that until mid-November, more than 99% of these were Delta cases. Both are variants in the Omicron family. Dr Meera Chand, UKHSA Director of Clinical an Emerging Infection, said: We continue to monitor the emergence of new variants and give them variant designations if they are sufficiently distinct to warrant separate epidemiological and laboratory assessment. The individuals who have tested positive and their contacts are all isolating. According to the ZOE study - conducted across Omicron and Delta waves for comparison - there are five key symptoms of the Omicron variant. Please make sure you follow all the available guidance. The updated risk assessment includes indicators for infection severity in both adults and children. ROCHESTER, Minn. The World Health Organization designated COVID-19 variant B.1.1.529, named omicron, a "variant of concern" on Nov. 26, 2021, and the first confirmed case in the U.S. was on Dec. 1, 2021. Can Nigeria's election result be overturned? A runny nose, gastrointestinal issues, headache and a skin rash are other common signs and symptoms. This new mutation dubbed BA.2.75 is concerning scientists because it appears to spread fast, bypassing the protection offered by COVID-19 vaccines and immunity from previous infection, the Associated Press reported Monday. Based on the CDC's genomic surveillance, the BA.2 or stealth Omicron subvariant is responsible for most new SARS-CoV-2 infections in the U.S. BA.2 is a subvariant of the original SARS-CoV-2 Omicron variant (B.1.1.529), along with BA.1.1 and BA.3. The full document and underlying data is available on GOV.UK. For example, there are still a small number of cases of other variants, such as Alpha, in the UK which would also result in S-gene dropout or there is a lower amount of virus present in the sample where S-gene dropout cannot be confirmed. Data for the devolved administrations will follow in due course. Dr Susan Hopkins, Chief Medical Advisor for UKHSA, said: Ongoing variant analysis is an important part of our pandemic response. Thanks to the expertise of scientists at UKHSA and partner organisations, were able to respond quickly to new variations of the virus. It is very likely that we will find more cases over the coming days as we are seeing in other countries globally and as we increase case detection through focused contact tracing. UKHSAwill continue to carry out laboratory and epidemiological investigations to better understand the characteristics of this variant. So, like the original omicron strain (BA.1), the primary symptoms of a mild BA.2 infection are a cough, fever, fatigue and possible loss of taste or smell. BQ.1 (V-22OCT-01) is a BA.5 sub-lineage which has been designated on the basis of rapid growth. For the first time, this data includes analysis on vaccine effectiveness 15+ weeks after the booster dose. The latest UK Health Security Agency (UKHSA) COVID-19 variant technical briefing, published today, includes updated epidemiological analysis which indicates that Omicron BA.5 has, as expected, become the dominant SARS-CoV-2 variant in the UK. Our exceptional vaccine rollout means the number of people severely affected by COVID-19 is low, and the UKs innovation and research has discovered life-saving treatments for those most at risk from COVID-19. The UK Health Security Agency (UKHSA) has published analyses of Omicron sub-lineage BA.2. This edition includes an update on the current circulating lineages, including several cases of Omicron BA.4 and BA.5 which have been detected in the UK. Omicron soon began branching off into a number of subvariants: BA.2 took off in the spring, and BA.5 came to dominate towards the end of the summer. Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, National flu and COVID-19 surveillance report, higher risk of becoming seriously ill from respiratory infections, including COVID-19, this data should be interpreted with caution, This assessment is based on analysis of UK data, data on Omicron cases is published regularly here, Six cases of the SARS-CoV-2 variant known as B.1.1.529, Investigation of SARS-CoV-2 variants of concern: variant risk assessments, Investigation of SARS-CoV-2 variants: technical briefings, Coronavirus (COVID-19): guidance for local government, let fresh air in if meeting others indoors, wear a face covering or a face mask, particularly if you are in crowded and enclosed spaces. The two most reported symptom of patients infected by the Stealth Omicron variant is -dizziness and fatigue. We continue to monitor all recombinants closely, routinely through our world-leading genomic surveillance and sequencing capability. Take a vaccine to protect yourself against COVID-19. Whilst there are insufficient data to quantify either vaccine effectiveness or risk of reinfection in the UK exactly, the observed growth, case distribution and early analyses in both South Africa and the UK are consistent with some loss of immune protection against infection. Since then, the Centers for Disease Control and Prevention (CDC) has classified two subvariants, BA.1.1 and BA.2. The public health advice is the same for all current variants. We also use cookies set by other sites to help us deliver content from their services. XD has not been identified in the UK to date, though 49 cases have been reported to global databases, the majority of these are in France. UKHSAis acting to get scientific information available as quickly as possible in order to inform the right balance of interventions to prevent transmission and protect lives. Work from home if you are able to, wear a mask indoors around other people, and ventilate indoor spaces well. Thanks to very high levels of vaccine coverage we already have a robust wall of defence against COVID-19 as new variants emerge. The total number of confirmed cases in England is now 5. Our continued genomic surveillance allows us to detect them and assess whether they are significant. The total number of confirmed cases in England is now 22. All 3 subvariants have spike protein mutations of L452 and elude immunity from prior BA1 infection. UKHSA scientists are urging anyone who has not had all the vaccines they are eligible for to make sure that they get them as soon as possible. We have also learnt that BA.2 has a slightly higher secondary attack rate than BA.1 in households. Previous updates were published by Public Health England. UKHSA, in partnership with scientific bodies across the globe, is constantly monitoring the status of SARS-CoV-2 variants as they emerge and develop worldwide. Dr Mary Ramsay, Head of Immunisation at UKHSA, said: These early estimates should be treated with caution but they indicate that a few months after the second jab, there is a greater risk of catching the Omicron variant compared to Delta strain. Data for Scotland, Wales and Northern Ireland is not included in the UKHSA Technical Briefing. The newest COVID variant taking the world by storm is Omicron's stealthy sub-variant BA.2, and it seems to have brought on a new barrage of gastrointestinal symptoms with it. The UK Health Security Agency (UKHSA) has published the latest Variant Technical Briefing. Data on this wont be available for several weeks. There is insufficient data to make any assessment of protection against severe disease, or to assess the severity of illness caused by Omicron. It remains vital that anyone with COVID-19 symptoms isolates and gets aPCRtest immediately. A detrimental change in biological properties (changes in transmissibility, severity or immune evasion) compared to the current dominant variant. This paper can be found as a pre-print, and the data is referred to in the latest vaccine surveillance report. This new UKHSA data on Omicron is promising while 2 doses of the vaccine arent enough, we know boosters offer significant protection against the variant and early evidence suggests this strain may be less severe than Delta. UKHSAs latest analysis suggests that Omicron BA.5 is growing 35.1% faster than Omicron BA.2, while Omicron BA.4 is growing approximately 19.1% faster. As I previously reported, omicron subvariants have a shorter incubation period, which is why the symptoms may appear earlier. The latest Omicron SARS-CoV-2 subvariant, which scientists have labeled BA.2.12.1, is on track to become the most virulent strain in the United States currently. UKHSAis acting to get scientific information available as quickly as possible in order to inform the right balance of interventions to prevent transmission and protect lives. An important question is whether BA.2 or BA.3 will become a new dominating "variant of concern". Spector shared a list of symptom prevalence from people who had tested positive for COVID, most of whom were estimated to have caught BA.2, he said. The latest data confirmed that among those who had received 2 doses of AstraZeneca, there was no effect against Omicron from 20 weeks after the second dose. Analysis from routine contact tracing data indicates that transmission is likely to be higher among contacts of BA.2 cases in households (13.4%) than those for contacts of other Omicron cases(10.3%) in the period 27 December 2021 to 11 January 2022. Once again, we urge everyone who is able to get a booster jab to come forward and do so. Work is underway to identify any links to travel to Southern Africa. A recombinant variant occurs when an individual becomes infected with 2 or more variants at the same time, resulting in a mixing of their genetic material within the patients body. The designation was made on the basis of increasing numbers of BA.2 sequences identified both domestically and internationally. Its critical that anyone with COVID-19 symptoms isolates and gets aPCRtest immediately. What are the symptoms of BA.2? Since BA.2 is a sub-strain of the Omicron variant, it is expected that its symptoms will be similar. Its critical that anyone with COVID-19 symptoms isolates and gets a PCR test immediately. Approximately half of PCR tests in the UK are able to detect SGTF. The analysis included very small numbers of cases as only a few people in the UK currently have this variant, meaning this data should be interpreted with caution until more cases have been studied. Based on the reports from doctors treating the Covid variant and patients battling. In addition, UKHSA has published data which shows the detection of cases exhibiting S-gene target failure (SGTF) in recent weeks across the country. Those are pretty similar to what people experience with a cold or other seasonal viruses. A NEW Covid-19 Omicron sub-variant is spreading across Ireland and is the most infectious strain yet. Lower back pain. There are differences in the populations that have received different vaccines. At this point it is not possible to determine where the sublineage may have originated. The Omicron variant of Covid-19 includes the lineages BA.1, BA.2, BA.3 and B.1.1.529. A study of 8,500 households and 18,000 individuals conducted by Denmark's SSI found that BA.2 was "substantially" more transmissible than BA.1. As previously published, data continues to show vaccine effectiveness against hospitalisation for Omicron remains high. Two-thirds with Omicron say they had Covid before. A further 3 cases have been identified in Scotland, bringing the total to 13. UKHSAis carrying out targeted testing at locations where the positive cases were likely to be infectious. Neither have currently been designated as variants of concern. In England, the infection rate increased in those aged 25 years to 49 years and those aged 70 years and over in the week ending 21 February 2023.
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